Common side effects of promethazine hydrochloride suppositories include dizziness, drowsiness, sleepiness, restlessness, blurred vision, dry mouth, stuffy nose, ringing in the ears, weight gain, swelling in hands or feet, impotence, trouble having an orgasm, or constipation.

Also to know is, how long does it take for a Phenergan suppository to kick in?

Remain lying down for a few minutes after using this medication, and avoid having a bowel movement for an hour or longer so the drug will be absorbed. The suppository is for rectal use only. For motion sickness, the first dose of promethazine should be used 30 to 60 minutes before beginning travel.

One may also ask, what are the side effects of Phenergan? Common Phenergan side effects may include:

  • drowsiness, dizziness;
  • ringing in your ears;
  • double vision;
  • feeling nervous;
  • dry mouth; or.
  • tired feeling, sleep problems (insomnia).

In this manner, how often can I take Phenergan suppository?

Phenergan (Promethazine HCl) Suppositories are for rectal administration only. The average dose is 25 mg taken before retiring; however, 12.5 mg may be taken before meals and on retiring, if necessary. Single 25-mg doses at bedtime or 6.25 to 12.5 mg taken three times daily will usually suffice.

How much do Phenergan suppositories cost?

The cost for Promethegan rectal suppository 12.5 mg is around $76 for a supply of 12 suppository, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Promethegan is available, see promethazine prices.

Related Question Answers

How do you put suppositories in without an applicator?

If you are inserting the tablet without an applicator, lie on your back with knees towards your chest, and place the suppository on the tip of your finger. Gently insert the suppository high into the vagina as far as it will comfortably go.

How long after putting a suppository can you poop?

This medicine should produce a bowel movement within 15 to 60 minutes after using the suppository. Do not use glycerin rectal more than once in a 24-hour period. Call your doctor if this medication does not cause you to have a bowel movement within 1 hour after use.

How long does promethazine 25 mg stay in your system?


Promethazine will be mostly out of your system in two to four days . The elimination half-life of a medication is the time it takes for blood levels of the medication to be reduced by half. For Promethazine the half-life is approximately 10 to 19 hours.

How long does a suppository take to absorb?

Carefully push the suppository, tapered end first, about 1 inch into your bottom. Close your legs and sit or lie still for about 15 minutes to let it dissolve.

Do suppositories stop vomiting?

Zofran suppositories contain ondansetron which is used to help stop the nausea (sick feeling) and vomiting which can occur after certain treatments. Zofran suppositories should only be used to treat the nausea and vomiting for which they have been prescribed.

How long does Phenergan last?

Promethazine is well absorbed from the gastrointestinal tract. Clinical effects are apparent within 20 minutes after oral administration and generally last four to six hours, although they may persist as long as 12 hours.

Will Phenergan stop vomiting?

Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and runny nose.

Is 50mg of Phenergan safe?

Phenergan in 12.5- to 25-mg doses for children and 50-mg doses for adults the night before surgery relieves apprehension and produces a quiet sleep. Phenergan Tablets and Phenergan Rectal Suppositories are contraindicated for children under 2 years of age.

Can you die from too much Phenergan?

People who experience heart rhythm irregularities and seizures are at highest risk for a serious outcome. Few people actually die from promethazine overdose.

Can you take two 25 mg Phenergan?

Typical dosage for active nausea and vomiting: 25 mg. Between 12.5 mg and 25 mg may be taken again every 4–6 hours, if needed. Typical dosage for preventing nausea and vomiting: 25 mg every 4–6 hours as needed.

Is it bad to take Phenergan every night?

Yes. If you take it for insomnia or take it at night time, promethazine will help you sleep. If you take it during the day for other conditions, such as allergies, it might cause daytime sleepiness, too.

Is Phenergan safe for long term use?

Phenothiazines such as promethazine can cause skin hyperpigmentation (darkening) but usually only after prolonged use. The effect usually is restricted to areas of the body exposed to sunlight. Thus, people who need longterm treatment with promethazine should either keep out of the sun or use effective sunscreens.

Is Phenergan bad for your liver?

Phenothiazines (Includes Phenergan) ↔ liver disease

In addition, the use of some phenothiazines has been associated with adverse hepatic effects including cholestatic jaundice and elevated liver enzymes, generally within the first few months of therapy.

Can Phenergan have the opposite effect?

Antihistamines, including promethazine (for example, Phenergan®) or trimeprazine (for example, Vallergan®), aren't recommended for helping children sleep, unless you use them under the supervision of your doctor. Antihistamines can also have the opposite effect, causing some children to become hyperactive.

How much Phenergan can I take?

Phenergan tablets are recommended for adults and children over 6 years of age. Phenergan elixir is recommended for children 2-5 years of age. Adults: One to three 25mg tablets as a single dose at night, or one to two 10mg tablets, two to three times daily.

How much does promethazine cost per pill?

Generic promethazine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. The lowest GoodRx price for the most common version of promethazine is around $10.00, 47% off the average retail price of $19.05.

What is the generic brand for promethazine?

Promethazine is the generic form of the brandname drug Phenergan, used as an antihistamine, sedative, and anti-nausea drug. Your doctor may also prescribe promethazine to relieve allergy symptoms like runny nose and watery, red eyes, or prevent and treat motion sickness.

What is promethazine gel?

Promethazine (also called Phenergan®) is a medicine called an antiemetic. It is used to treat nausea and vomiting. Promethazine topical gel is a way of giving your child this nausea medicine. When the gel is put on your child's skin, a small amount of the medicine is absorbed through the skin.