What does indolent lymphoma mean?

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are both indolent types of cancer. They may affect the blood, bone marrow, or lymph nodes.

Patients who suffer from indolent lymphoma live an average of 10 to 15 years or longer after diagnosis due to its slow-growing characteristics. In fact, even when diagnosed early, in some cases physicians decide to watch and wait instead of a more aggressive treatment approach.

The combinations of chemotherapy drugs most often used to treat limited-stage indolent NHL are: CHOP – cyclophosphamide (Cytoxan, Procytox), doxorubicin (Adriamycin), vincristine (Oncovin) and prednisone. R-CHOP – CHOP with rituximab (Rituxan) CVP – cyclophosphamide, vincristine and prednisone.

Your healthcare provider may tell you that a tumor is indolent. That means that it will grow slowly, and you have some time to make decisions about how you will treat it. Likewise, an ulcer may be considered indolent, meaning it is present, but not causing pain.

Medical Definition of indolent 1 : causing little or no pain an indolent tumor. 2a : growing or progressing slowly leprosy is an indolent infectious disease.

Mantle cell lymphoma (MCL) is an aggressive disease, with poor prognosis and a limited survival. However, some patients with indolent MCL can survive beyond 7~10 years. These patients remain largely asymptomatic and can be in observation for a long time without any treatment.

Low grade lymphoma, also known as indolent lymphoma, is usually very slow growing and most often incurable, though many patients respond positively to treatment. Low grade lymphomas can be localized in the initial stages, or in severe cases it can spread to different sites.

Lymphoma warning signs include swollen lymph nodes, fever, chills, weight loss, shortness of breath, drenching night sweats, tiredness, and swelling in the abdomen. Lymphoma is a cancer of certain cells that are part of the body’s immune system called lymphocytes.

Indolent CLL is slow growing and can remain stable without treatment for years. If your CLL is indolent, it means that there are an increased number of lymphocytes in your blood, but your other blood cell counts are normal or only slightly below normal. Your physician may recommend “watchful waiting” in this situation.

Most people with indolent non-Hodgkin lymphoma will live 20 years after diagnosis. Faster-growing cancers (aggressive lymphomas) have a worse prognosis. They fall into the overall five-year survival rate of 60%.

• Extranodal marginal zone B-cell lymphoma, also known as mucosa-associated lymphoid tissue (MALT) lymphoma: This is the most common type of marginal zone lymphoma. …
• Nodal marginal zone B-cell lymphoma: This is a rare disease.

Sometimes a provider may choose to wait and observe the involved lymph nodes, which will usually go away on their own if a temporary infection is causing the swelling. (However, some lymphomas may go away and appear to be benign, only to reappear at a later time.)

Non-Hodgkin lymphoma is called ‘low grade’ or ‘indolent’ when the lymphoma cells are dividing slowly. Low-grade non-Hodgkin lymphoma can develop over a long period of time and is often at an advanced stage by the time it is diagnosed.

Limit your intake of saturated (‘sat’) fats. This type of fat is found in foods such as butter, meat, cakes, and many processed foods, such as sausages and crisps. It’s fine to have a little bit of saturated fat. Women should eat no more than 20g a day; men should eat no more than 30g a day.

: inclination to laziness : sloth.

In this page you can discover 36 synonyms, antonyms, idiomatic expressions, and related words for indolent, like: lazy, idle, busy, lethargic, listless, dronish, inactive, slothful, sluggish, active and inert.

Indolent wounds are characterised by a rim of infected, necrotic tissue in which leucocytes and macrophages are unable to function effectively through lack of oxygen. A suitable dressing changed frequently can bring about mild debridement and re-establish the conditions for healing.

Standard upfront options typically include chemotherapy plus rituximab (Rituxan), and can include autologous stem cell transplant and rituximab maintenance as well. But chemotherapy regimens are associated with high rates of toxicity, and treatment-related secondary malignancies remain a concern.

Leukemic mantle cell lymphoma limited to blood and bone marrow is an indolent variant characterized by mild-moderate lymphocytosis, interstitial low-level bone marrow involvement, simple karyotype, kappa light chain expression, cyclin D1 expression with lack of SOX11, and slow or absent clinical progression.

Does mantle cell lymphoma run in families? For most patients, the cause of the disease is unknown, but rates are higher among farmers and people from rural areas.

Angioimmunoblastic lymphoma (AITL) is a rare type of non-Hodgkin lymphoma (NHL). It is a high grade (aggressive) lymphoma that affects blood cells called T cells.

There are very few cancers for which doctors will use the word ‘cure’ right off the bat, but Hodgkin lymphoma (HL), the most common cancer diagnosis among children and young adults, comes pretty darn close: Ninety percent of patients with stages 1 and 2 go on to survive 5 years or more; even patients with stage 4 have …

Myth #1: A diagnosis of lymphoma is a death sentence. Treatments are very effective for some types of lymphoma, particularly Hodgkin’s lymphoma, when detected early on. In fact, medical advances over the last 50 years have made Hodgkin’s lymphoma one of the most curable forms of cancer.

Lymphoma is a type of tumor that starts in white blood cells called lymphocytes, and when it is not cancerous, it is called benign lymphoma, pseudolymphoma, or benign lymphoid hyperplasia (BLH).

Life expectancy for this disease The average age of those who are diagnosed with indolent lymphoma is about 60. It affects both men and women. The average life expectancy after diagnosis is approximately 12 to 14 years.

Low-Grade Lymphoma These grow so slowly that patients can live for many years mostly without symptoms, although some may experience pain from an enlarged lymph gland. After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms.

The most common sign of lymphoma is a lump or lumps, usually in the neck, armpit or groin. These lumps are swollen lymph nodes, sometimes known as ‘glands’. Usually, they’re painless. Fatigue is different to normal tiredness.

Lymphomas can start anywhere in the body where lymph tissue is found. The major sites of lymph tissue are: Lymph nodes: Lymph nodes are bean-sized collections of lymphocytes and other immune system cells throughout the body, including inside the chest, abdomen, and pelvis.

The best way to find HL early is to be on the lookout for possible symptoms. The most common symptom is enlargement or swelling of one or more lymph nodes, causing a lump or bump under the skin which usually doesn’t hurt. It’s most often on the side of the neck, in the armpit, or in the groin.

This information is about chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL). CLL and SLL are different forms of the same illness. They are often grouped together as a type of slow-growing (low-grade or indolent) non-Hodgkin lymphoma.

Smudge cells are remnants of cells that lack any identifiable cytoplasmic membrane or nuclear structure. Smudge cells, also called basket cells, are most often associated with abnormally fragile lymphocytes in disorders such as chronic lymphocytic leukemia (CLL).

Is Hodgkin’s worse than non-Hodgkin’s lymphoma? The progression of Hodgkin’s lymphoma is typically more predictable than that of non-Hodgkin’s lymphoma. The prognosis of Hodgkin’s lymphoma is also better than that of non-Hodgkin’s lymphoma since non-Hodgkin’s lymphoma is often diagnosed at a more advanced stage.

The prognosis of NHL can be good but depends on the type of lymphoma, the extent of spread (staging), and response to therapy. A health care provider will discuss the prognosis with the patient. The overall five-year survival rate for people with NHL is 71%, while the overall 10-year survival rate is 60%.

Many people with a high-grade non-Hodgkin’s lymphoma will be cured. Therefore, the usual aim of treatment for high-grade non-Hodgkin’s lymphoma is to cure it. A cure is most likely in cases which are at an early stage. However, there is still a good chance of a cure even with those in more advanced stages.

Hodgkin lymphoma is considered one of the most treatable cancers, with more than 90 percent of patients surviving more than five years. Most patients with Hodgkin lymphoma live long and healthy lives following successful treatment.

There is no evidence that stress can make lymphoma (or any type of cancer) worse. Remember: scientists have found no evidence to suggest that there’s anything you have, or have not done, to cause you to develop lymphoma.

It’s very important to go to all of your follow-up appointments, because lymphoma can sometimes come back even many years after treatment. Some treatment side effects might last a long time or might not even show up until years after you have finished treatment.

Family history. Lymphoma is not passed on from parent to child (inherited). Most people who have a close family member with lymphoma or another blood cancer do not develop lymphoma themselves.

If left untreated, the disease will lead to death. If you decline life-saving treatment, you can choose to get support from palliative care (a medical team that manages your symptoms and pain).