The foods to avoid include: aged cheeses, avocados, bananas, raisins, sour cream, soy sauce, some sausages and meats, including liver; some fish, including skipjack, tropical fish and tuna, beer and red wine. You should restrict alcohol consumption while taking isoniazid because it boosts your risk for liver problems.
What foods should you avoid with an upset stomach? are eggs good for an upset stomach.

What foods should you avoid when taking isoniazid?

You may need to avoid certain foods while you are taking isoniazid. This includes red wine, aged cheese, dried meats, and tuna or other types of fish.

Can I eat cheese while taking isoniazid?

Patients should be advised to avoid foods containing tyramine (e.g., aged cheese, cured meats such as sausages and salami, fava beans, sauerkraut, soy sauce, beer, or red wine) or histamine (e.g., skipjack, tuna, mackerel, salmon) during treatment with isoniazid.

Can I drink coffee while taking isoniazid?

You can take your medicine with milk, water, juice, soda, coffee or tea. If your medicine causes upset stomach, take it with food. If you are taking an antacid (like Maalox, Mylanta), take it 1 hour before or 2 hours after taking your INH.

How do I reduce the side effects of isoniazid?

It is important that you do not miss any doses. Your doctor may also want you to take pyridoxine (e.g., Hexa-Betalin, vitamin B 6) every day to help prevent or lessen some of the side effects of isoniazid.

What vitamins should I take with isoniazid?

Vitamin B6 (pyridoxine) supplementation during isoniazid (INH) therapy is necessary in some patients to prevent the development of peripheral neuropathy.

What happens if you drink alcohol while taking isoniazid?

Avoid alcohol while taking isoniazid. Alcohol may increase the risk of damage to the liver during isoniazid treatment. Alcohol can also cause isoniazid side effects to get worse. Contact your doctor if you experience flushing, chills, headache, nausea, vomiting, and diarrhea.

Does isoniazid cause numb feet?

Damage to nerves (peripheral neuropathy) may occur with isoniazid and cause numbness and tingling of the hands or feet (parethesia). Other rare side effects related to the nervous system include: Encephalopathy (inflammation of the brain) Optic neuritis (inflammation of the nerve coming from the eye)

How long should isoniazid be taken?

WHO recommends isoniazid taken at a daily dose of 5 mg/kg (maximum 300 mg) for at least six months, and ideally for nine months.

Does isoniazid turn urine orange?

Isoniazid and rifampin may cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (a yellow, orange, red, or brown color). This side effect is usually not harmful. However, soft contact lenses may be permanently stained if you wear them while taking isoniazid and rifampin.

Can isoniazid cause weight gain?

Headache, poor concentration, weight gain, poor memory, insomnia, and depression have all been associated with isoniazid use. All patients and healthcare workers should be aware of these serious side effects, especially if suicidal ideation or behavior are suspected.

Can isoniazid cause hair loss?

Isoniazid is a safe and very effective antituberculosis drug. Antimitotic agents routinely cause alopecia. Drug-induced alopecia is usually reversible upon withdrawal of the drug. Isoniazid, thiacetazone and ethionamide are the antituberculosis drugs which have been associated with alopecia.

How does isoniazid affect the liver?

Chronic INH hepatotoxicity results in the induction of hepatocyte apoptosis, with associated disruption of mitochondrial membrane potential and DNA strand breaks. The most likely biochemical mechanism is that the metabolism of INH produces reactive metabolites that bind and damage cellular macromolecules in the liver.

What is the most common side effect of isoniazid?

Common side effects may include: numbness, tingling, or burning pain in your hands or feet; nausea, vomiting, upset stomach; or. abnormal liver function tests.

Does isoniazid increase blood pressure?

Isoniazid may interact with foods containing tyramine/histamine (such as cheese, red wine, certain types of fish). This interaction may cause increased blood pressure, flushing of the skin, headache, dizziness, or fast/pounding heartbeat. Tell your doctor right away if any of these symptoms occur.

Can I take ibuprofen with isoniazid?

No interactions were found between ibuprofen and isoniazid. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

How does isoniazid cause neuropathy?

The isoniazid-induced peripheral neuropathy occurring in adult tuberculous patients results from a deficiency of biologically active pyridoxine. The deficiency is caused by the combination of isoniazid and pyridoxine to form a hydrazone which is excreted in the urine.

Is Steam Good for TB patients?

Apart from Covid-19, Sempio also discourages steam inhalation with patients suffering from an infectious condition like tuberculosis where the possibility of generating infectious droplets is high.

Why do you give vitamin B6 with isoniazid?

Isoniazid can interfere with the activity of vitamin B6. Vitamin B6 supplementation is recommended, especially in people with poor nutritional status, to prevent development of isoniazid-induced peripheral neuritis (inflamed nerves). One case is reported in which injectable vitamin B6 reversed isoniazid-induced coma.

Is red wine good for TB patient?

Organic compound found in red wine boosts the body’s ability to fight drug-resistant TB. An organic compound found in grape skins can stimulate the mouse immune system to fight even the most persistent tuberculosis strains.

Why do you have to take isoniazid on an empty stomach?

MUNICH — When first-line tuberculosis (TB) drugs are taken with food, there is a reduction in maximum plasma concentration and bioavailability of the drug than when taken on an empty stomach, according to the results of a new pharmacokinetic study.

How do you know if TB treatment is working?

Physical Signs That TB Treatment Is Working Overall improvement in the way one feels. Weight gain. Increased appetite. Improvement in strength and stamina.

Can isoniazid cause muscle pain?

Peripheral neuropathy is a rare adverse effect associated with isoniazid, and it occurs after the prolonged use of this drug [1]. This usually presents with paresthesias which can be accompanied by muscle aches, occasionally muscular weakness, and can progress to more severe symptoms such as ataxia [1].

What should I take with isoniazid?

If you are taking isoniazid by mouth and it upsets your stomach, take it with food. Antacids may also help. However, do not take aluminum-containing antacids within 1 hour of taking isoniazid. They may keep this medicine from working properly.

How much water should a TB patient drink?

I am a T.B. patient, doctor has advised me to take food 6 time and 6 litres of water in a day.

Does Tamsulosin make you sleepy?

Taking too much tamsulosin can lead to a decrease in your blood pressure and an increase in your heart rate. You may feel drowsy, faint and lightheaded.

Can isoniazid cause blood clots?

This medicine may cause blood clotting problems, which may lead to bleeding.

Why is my pee bright yellow?

Bright yellow urine is a sign of excess B-vitamins in the body, including B-2 and B-12, although this condition is harmless. Taking B-vitamin supplements can lead to urine of this color. The yellow color darkens as the concentration of the urine increases. Concentration refers the proportion of waste products to water.

How does isoniazid work in the body?

It works by killing the bacteria that cause the disease. The exact mechanism of action of isoniazid is unknown, but it is thought to prevent the tuberculosis bacteria from making substances called mycolic acids, which are needed to form the cell walls of the bacteria.

Is hair fall symptom of TB?

Scarring or cicatricial alopecia. However, other types of scarring that may cause hair loss can be caused by diseases. These include lupus, bacterial or fungal skin infections, lichen planus, sarcoidosis, tuberculosis, or skin cancer.

Can hair regrow after TB treatment?

The hair regrowth was observed after 3 weeks of isoniazid withdrawal with complete recovery after 6 weeks. The subsequent treatment period was uneventful. The patient was cured from pulmonary tuberculosis after 6 months of anti-tuberculosis chemotherapy. The long-term follow-up was also uneventful for next 5 years.

What is the alternative of isoniazid?

Rifampicin for three to four months may give quite similar results to isoniazid for six months in preventing TB, and may cause fewer side effects. As the treatment period with rifampicin is shorter, it may result in more people completing treatment.

What are the symptoms of liver toxicity?

  • Yellowing of the skin and whites of the eyes (jaundice)
  • Itching.
  • Abdominal pain in the upper right portion of the abdomen.
  • Fatigue.
  • Loss of appetite.
  • Nausea and vomiting.
  • Rash.
  • Fever.
How does isoniazid cause neurotoxicity?

The increased sensitivity of the dialysis population to isoniazid neurotoxicity is predominantly due to abnormal metabolism of pyridoxine resulting in low serum levels of the active metabolite, pyridoxal phosphate.