What is the drug of choice for glaucoma?

• Bimatoprost (Lumigan)
• Latanoprost (Xalatan)
• Tafluprost (Zioptan)
• Travoprost (Travatan Z)

Bimatoprost, based on the efficacy, safety and ease of use, has been approved as a first-line treatment for glaucoma, and well positioned among the first-choices in glaucoma medical therapy.

DURYSTA™ Bimatoprost Implant The US Food and Drug Administration (FDA) recently approved Allergan’s new drug application for DURYSTA™; the first intracameral, biodegradable sustained-release implant indicated to reduce intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT).

Tilt your head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink.

Travoprost/Timolol is a combination of two active substances, travoprost and timolol. Like other medicines administered to the eyes, travoprost and timolol (a beta-blocker) are absorbed into the blood.

Travoprost ophthalmic comes as a solution (liquid) to instill in the eye. It is usually instilled in the affected eye(s) once a day in the evening. To help you remember to use travoprost, use it around the same time every day.

Travoprost (Travatan Z) takes about 2 hours to kick in and 12 hours to reach maximum effect. Your eye pressure is best controlled if you use this medication once a day in the evening consistently (without missing a dose).

Conclusions: Travoprost (0.0015% and 0.004%), a highly selective, potent prostaglandin F (FP) receptor agonist, is equal or superior to latanoprost and superior to timolol in lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

There was no difference between travoprost and latanoprost. The most common treatment-related adverse event was conjunctival hyperemia. Intensity of ocular hyperemia was greater in the travoprost group compared with the latanoprost and DTFC groups (p<0.05).

After using TRAVATAN Store Travatan Eye Drops in a cool dry place where the temperature stays below 30°C. It is not necessary to store Travatan Eye Drops in the refrigerator, but it is acceptable if you prefer to instil cold drops.

The Travatan brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

Travatan Z is available in a generic form called travoprost. A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be as safe and effective as the original drug.

• Antihistamines and decongestants.
• Asthma medicines.
• Motion sickness medicines.
• Some medicines used to treat depression (tricyclic antidepressants)

Interactions between your drugs Using latanoprost ophthalmic together with travoprost ophthalmic may reduce the pressure-lowering effects of these medications in the eye. Talk to your doctor if you have any questions or concerns. You may need more frequent eye examinations to safely use these medications together.

Latanoprost ophthalmic solution is available as a generic drug and a brand-name drug. Brand name: Xalatan. This drug is only available as an ophthalmic solution (eye drop). Latanoprost is used to treat open-angle glaucoma and ocular hypertension.

Latanoprost should be used cautiously in patients with renal disease (e.g., renal failure, renal impairment) or hepatic disease. There have been no studies on safe use in these patients.

Timolol/latanoprost is used is indicated in adults (including the elderly) for the reduction of intraocular pressure (IOP) in patients with open angle glaucoma and ocular hypertension who are insufficiently responsive to topical beta-blockers or prostaglandin analogues.

Travoprost eye drops are used to treat increased pressure in the eye caused by open-angle glaucoma or hypertension of the eye. Both conditions are caused by high pressure in the eye which can lead to pain or vision changes. This medicine is a prostaglandin.

How to store travoprost eye drops. Eye drops can be used for four weeks once the bottle has been opened. Even if there is still some solution remaining after this time, throw it away and use a new bottle. This will help to prevent the risk of eye infections.

December 19, 2019 – Apotex and Mylan launched AT-rated generic versions of Alcon’s Travatan-Z (travoprost) ophthalmic solution..

These results suggest that travoprost remains effective for at least 12 weeks after the laminated packaging has been opened.

TRAVATAN Z® (travoprost ophthalmic solution) 0.004% is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. The recommended dosage is one drop in the affected eye(s) once daily in the evening.

Specifically, diabetic patients treated by Metformin had a 25% lower risk to develop open-angle glaucoma. In addition, previous animal experiments have preliminarily shown that Metformin can play a neuroprotective role by activating AMPK kinase, regulating methylation levels and promoting ganglion cell survival.

• Coffee. Coffee has been shown to increase intraocular pressure (IOP) and cause it to remain elevated for at least 90 minutes. …
• Water. …
• Alcohol. …
• AREDS supplements. …
• Omega 3/6 supplements. …
• Vitamins. …
• Marijuana. …
• Nitrate rich leafy greens.