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RotaTeq® (Rotavirus Vaccine, Live, Oral, Pentavalent) is indicated for the prevention of rotavirus gastroenteritis in infants and children caused by Types G1, G2, G3, G4, and G9 when administered as a 3-dose series to infants between the ages of 6 to 32 weeks.
Both are live attenuated vaccines given orally to infants, but the component vaccine viruses differ. Rotarix (GlaxoSmithKline) contains 1 strain of attenuated human rotavirus (G1P strain). It protects against non-G1 serotypes based on other shared epitopes.
Pneumococcal conjugate vaccine: Synflorix given at 6 weeks, 3.5 months and 5.5 months of age. Infants received IM vaccinations into the right anterolateral thigh. Rotavirus vaccine: Rotarix. Two doses given two months apart orally.
RotaTeq* is a live, oral pentavalent vaccine that contains 5 live reassortant rotaviruses. RotaTeq is a pale yellow clear liquid that may have a pink tint. The rotavirus parent strains of the reassortants were isolated from human and bovine hosts.
Rotarix is a live, monovalent, human attenuated vaccine given in 2 doses (one course) at 2 and 4 months of age. RotaTeq is a live, pentavalent, human–bovine reassortant vaccine given in 3 doses (one course) at 2, 4 and 6 months of age.
RotaTeq is a vaccine manufactured by Merck and Co. Inc., (Merck) licensed by FDA in 2006 for the prevention of rotavirus gastroenteritis in infants 6 weeks to 32 weeks of age.
Rotarix is a live oral rotavirus vaccine developed from a single protective human strain following multiple passages in tissue culture to attenuate the strain.
There are four categories of vaccines in clinical trials: whole virus, protein subunit, viral vector and nucleic acid (RNA and DNA). Some of them try to smuggle the antigen into the body, others use the body’s own cells to make the viral antigen.
Both rotavirus vaccines are administered orally, by putting drops in the infant’s mouth. Each requires multiple doses: RotaTeq® (RV5) is given in three doses at 2 months, 4 months, and 6 months of age. Rotarix® (RV1) is given in two doses at 2 months and 4 months of age.
Prevenar 13 is a conjugate vaccine that helps provide protection against 13 serotypes of the bacterium, Streptococcus pneumoniae; a bacterium responsible for causing infection which can be grouped into categories of invasive and non invasive disease.
Synflorix is a vaccine that protects against infections caused by S. pneumoniae. Vaccines work by ‘teaching’ the immune system (the body’s natural defences) to defend the body against the infection.
Examples of stabilisers include sugars such as lactose and sucrose, amino acids such as glycine and monosodiumglutamate (salts of amino acids), proteins such as recombinant human albumin (Recombumin®) derived from baker’s yeast or fetal bovine (cow) serum and gelatin, partially hydrolysed collagen usually of porcine ( …
RotaTeq is an oral vaccine used to help prevent rotavirus infection in children. Rotavirus infection can cause fever, vomiting, and diarrhea that can be severe and can lead to loss of body fluids (dehydration), hospitalization and even death in some children.
The majority of the IS cases occurred in infants who were 4 months old or older at first vaccination. * human-bovine rotavirus reassortants (live), produced in Vero cells. Manufacturing process The active substance is manufactured at West Point, Pennsylvania, USA.
OralRotarix® vaccine must be administered ORALLY without mixing with any other oral vaccine or solution. Rotarix® must not be given via a nasogastric tube as this will reduce the efficacy.
The vaccine is over 85% effective at protecting against severe rotavirus infection in the first two years of life.
Pediarix™ is a combination product containing DTaP, hepatitis B, and inactivated polio vaccines.
According to the package inserts the maximum age for a dose of RotaTeq is 32 weeks and the maximum age for Rotarix is 24 weeks. According to ACIP recommendations the maximum age for a dose of rotavirus vaccine is 8 months 0 days.
Infants should get rotavirus vaccine to protect against rotavirus disease. There are two rotavirus vaccines licensed for use in infants in the United States: RotaTeq® (RV5), which is given in three doses at 2 months, 4 months, and 6 months of age.
This vaccine is used to prevent a certain virus infection (rotavirus) in infants and young children. Rotavirus can cause fever, vomiting, and diarrhea.
What is fractional dose IPV (fIPV)? A fractional dose of IPV is a smaller dose of the same vaccine, equal to 1/5 of a standard dose. Studies show that 2 doses of fractional dose IPV administered by intradermal injection produce an even stronger immune response than a single full IPV dose. 1.
The BCG vaccine protects against tuberculosis, which is also known as TB. TB is a serious infection that affects the lungs and sometimes other parts of the body, such as the brain (meningitis), bones, joints and kidneys.
Toxoid vaccines use a toxin (harmful product) made by the germ that causes a disease. They create immunity to the parts of the germ that cause a disease instead of the germ itself. That means the immune response is targeted to the toxin instead of the whole germ.
Examples of currently available live, attenuated vaccines against viral infections include measles, mumps, rubella (MMR), cowpox, yellow fever, influenza (FluMist®) intranasal vaccine), and oral polio vaccine. Live, attenuated bacterial vaccines include tuberculosis, BCG, and oral typhoid vaccine.
Toxoids are used extensively in the production of vaccines, the most prominent examples being the toxoids of diphtheria and tetanus, which are often given in a combined vaccine. Toxoids used in modern vaccines are commonly obtained by incubating toxins with formaldehyde at 37° C (98.6° F) for several weeks.
Hib vaccine is usually given in 3 or 4 doses (depending on brand). Infants will usually get their first dose of Hib vaccine at 2 months of age and will usually complete the series at 12–15 months of age.
Two rotavirus vaccines are currently licensed for infants in the United States: RotaTeq® (RV5) is given in 3 doses at ages 2 months, 4 months, and 6 months. Rotarix® (RV1) is given in 2 doses at ages 2 months and 4 months.
For intramuscular injections in infants, children and adults, therefore, a 25mm 23G (blue) or 25mm 25G (orange) needle should be used. Only in pre-term or very small infants is a 16mm needle suitable for IM injection.
Pneumococcal conjugate vaccine (PCV) is used to vaccinate children under 2 years old as part of the NHS vaccination schedule. It’s known by the brand name Prevenar 13. Pneumococcal polysaccharide vaccine (PPV) is given to people aged 65 and over and people at high risk because they have long-term health conditions.
MENVEO is a solution for intramuscular injection supplied as a lyophilized MenA conjugate vaccine component to be reconstituted with the accompanying MenCYW-135 liquid conjugate vaccine component. A single dose, after reconstitution, is 0.5 mL.
PREVNAR 20™ is a vaccine indicated for active immunization for the prevention of pneumonia and invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in adults 18 years of age and older.
The main difference between Pneumovax 23 and Prevnar 13 is how many different types of bacteria they target. Pneumovax 23 protects against 23 types of pneumococcal bacteria and is used in adults, while Prevnar 13 protects against 13 types of pneumococcal bacteria, and was designed primarily for children.
Easy Six Vaccine is a vaccine to protect infants and toddlers against diphtheria, haemophilus influenzae type b disease, pertussis, tetanus, and polio. It helps develop immunity against the mentioned diseases by initiating a mild infection.
Synflorix (PCV10) and Prevenar 13 (PCV13) are conjugate vaccines. » Polysaccharide (sugar) molecules from the outside of pneumococcal bacteria have been attached (conjugated) to a protein to make them better at stimulating the immune system.
The live, attenuated viral vaccines currently available and routinely recommended in the United States are MMR, varicella, rotavirus, and influenza (intranasal). Other non-routinely recommended live vaccines include adenovirus vaccine (used by the military), typhoid vaccine (Ty21a), and Bacille Calmette-Guerin (BCG).
Human serum albumin (0.3 mg/dose) is contained in measles vaccine (Attenuvax; Merck and Co, West Point, PA); mumps vaccine (Mumpsvax; Merck and Co); rubella vaccine (Meruvax; Merck and Co); and measles, mumps, and rubella vaccine (MMRII; Merck and Co).
- How Vaccines Work.
- Johnson & Johnson’s Janssen.
- mRNA Vaccines.
- Viral Vector Vaccines.
Manufacturer: Merck Shark & Dohme Corp.
The risk of serious side effects of RotaTeq is low. Call your doctor immediately if your child experiences serious side effects of RotaTeq such as seizure, severe diarrhea, high fever (greater than 102 degrees F/39 degrees C, redness of skin or eyes, pain in their stomach or chest, or pain while urinating.