Kleine-Levin syndrome is an extremely rare disorder characterized by the need for excessive amounts of sleep (hypersomnolence), excessive eating (compulsive hyperphagia), and behavioral abnormalities.
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What are the symptoms of Kleine-Levin Syndrome?

Symptoms occur as “episodes,” typically lasting a few days to a few weeks. Episode onset is often abrupt, and may be associated with flu-like symptoms. Excessive food intake, irritability, childishness, disorientation, hallucinations, and an abnormally uninhibited sex drive may be observed during episodes.

Which of the following symptoms is associated with Kleine-Levin Syndrome also known as Sleeping Beauty disorder?

Kleine-Levin syndrome (KLS) is a rare disorder that causes recurring periods of excessive sleepiness. In some cases, this means up to 20 hours a day are spent sleeping. For this reason, the condition is commonly referred to as “sleeping beauty syndrome.” KLS can also produce changes in behavior and confusion.

What are the symptoms of sleeping beauty syndrome?

  • Sleeping most of the day and night.
  • Abrupt onset, sometimes accompanied by flu-like symptoms.
  • Spaciness or childishness.
  • Lethargy.
  • Excessive food intake or food cravings while awake.
  • Irritability.
  • Depressed mood.
  • Disorientation.
How is KLS diagnosed?

To be diagnosed with KLS, a person must meet first the criteria for recurrent hypersomnia: Episodes of excessive sleepiness lasting between two days and five weeks. Episodes occur at least once every 18 months and often more frequently. Normal behavior and cognition between episodes.

What is Frohlich syndrome?

Froehlich syndrome is characterized by increased or excessive eating that leads to obesity, small testes, and a delay in the onset of puberty. It is also common for children with Froehlich syndrome to experience the delay in physical growth and the development of secondary sexual characteristics.

What is a Dyssomnia?

Parasomnia sleep disorders cause abnormal activities during sleep, such as sleep terrors or sleep walking. Dyssomnia sleep disorders cause trouble falling asleep or staying asleep. Perhaps the most well known dyssomnia is obstructive sleep apnea.

What are the 5 types of sleep disorders?

  • Restless Legs Syndrome (RLS) RLS is a condition that causes your legs to move or shake because of an unpleasant sensation. …
  • Insomnia. …
  • REM Sleep Behavior Disorder (RBD) …
  • Sleep Apnea. …
  • Narcolepsy.
What is the rarest sleep disorder?

Kleine-Levin Syndrome (KLS), also known as “Sleeping Beauty” syndrome, is a rare neurological disorder characterised by recurrent bouts of hypersomnolence (excessive sleeping) along with cognitive and behavioural problems during wakefulness.

What is the sleeping beauty syndrome?

Abstract. Kleine–Levin syndrome (KLS), also called “Sleeping beauty syndrome” is a rare, disorder predominantly reported in adolescent males, characterized by recurrent episodes of hypersomnia and to various degrees, hyperphagia, cognitive disturbances, and hypersexuality.

Is Sleeping Beauty syndrome narcolepsy?

Once referred to as “Sleeping Beauty,” Suzanne Reagan discovered her family history of narcolepsy also affected her, after undergoing a sleep study at Cleveland Clinic.

What causes sleeping for days at a time?

The most common causes of excessive daytime sleepiness are sleep deprivation, obstructive sleep apnea, and sedating medications. Other potential causes of excessive daytime sleepiness include certain medical and psychiatric conditions and sleep disorders, such as narcolepsy.

Is hypersomnia an autoimmune disorder?

Autoimmune diseases, especially lupus and rheumatoid arthritis, are often associated with hypersomnia. Morvan’s syndrome is an example of a rarer autoimmune illness that can also lead to hypersomnia.

How rare is KLS?

KLS is very rare, occurring at a rate of 1 in 1 million, which limits research into genetic factors. The condition primarily affects adolescent males, though females can also be affected and the age of onset varies.

How is KLS treated?

There is no specific, definitive treatment to cure or control KLS. Some aspects of the disease can be managed with medication, such as stimulants to combat the EDS, but this is most effective only once the episodes have already decreased in severity.

What is the outcome of KLS patients?

Cognitive Disturbances Between episodes, majority of patients were described as totally normal. In a few cases reported, academic decline and a mild, long-lasting memory dysfunction between episodes. [21,22] The possibility of residual dysfunction after KLS termination was also reported.